diff --git a/.gitignore b/.gitignore
index 46dcf84b43a..3946cc96e54 100644
--- a/.gitignore
+++ b/.gitignore
@@ -38,6 +38,7 @@ platform/windows/godot_res.res
 # Ninja build files
 build.ninja
 .ninja
+run_ninja_env.bat
 
 # Generated by Godot binary
 .import/
diff --git a/core/crypto/SCsub b/core/crypto/SCsub
index ac79e10d19a..a6defdfdabc 100644
--- a/core/crypto/SCsub
+++ b/core/crypto/SCsub
@@ -21,9 +21,9 @@ if is_builtin or not has_module:
 # to make a "light" build with only the necessary mbedtls files.
 if not has_module:
     # Minimal mbedTLS config file
-    env_crypto.Append(
-        CPPDEFINES=[("MBEDTLS_CONFIG_FILE", '\\"thirdparty/mbedtls/include/godot_core_mbedtls_config.h\\"')]
-    )
+    config_path = "thirdparty/mbedtls/include/godot_core_mbedtls_config.h"
+    config_path = f"<{config_path}>" if env_crypto["ninja"] and env_crypto.msvc else f'\\"{config_path}\\"'
+    env_crypto.Append(CPPDEFINES=[("MBEDTLS_CONFIG_FILE", config_path)])
     # Build minimal mbedTLS library (MD5/SHA/Base64/AES).
     env_thirdparty = env_crypto.Clone()
     env_thirdparty.disable_warnings()
@@ -46,9 +46,9 @@ if not has_module:
     env.core_sources += thirdparty_obj
 elif is_builtin:
     # Module mbedTLS config file
-    env_crypto.Append(
-        CPPDEFINES=[("MBEDTLS_CONFIG_FILE", '\\"thirdparty/mbedtls/include/godot_module_mbedtls_config.h\\"')]
-    )
+    config_path = "thirdparty/mbedtls/include/godot_module_mbedtls_config.h"
+    config_path = f"<{config_path}>" if env_crypto["ninja"] and env_crypto.msvc else f'\\"{config_path}\\"'
+    env_crypto.Append(CPPDEFINES=[("MBEDTLS_CONFIG_FILE", config_path)])
     # Needed to force rebuilding the core files when the configuration file is updated.
     thirdparty_obj = ["#thirdparty/mbedtls/include/godot_module_mbedtls_config.h"]
 
diff --git a/modules/mbedtls/SCsub b/modules/mbedtls/SCsub
index 4b8f65d8ffa..04d26f99424 100644
--- a/modules/mbedtls/SCsub
+++ b/modules/mbedtls/SCsub
@@ -100,9 +100,9 @@ if env["builtin_mbedtls"]:
     thirdparty_sources = [thirdparty_dir + file for file in thirdparty_sources]
 
     env_mbed_tls.Prepend(CPPPATH=["#thirdparty/mbedtls/include/"])
-    env_mbed_tls.Append(
-        CPPDEFINES=[("MBEDTLS_CONFIG_FILE", '\\"thirdparty/mbedtls/include/godot_module_mbedtls_config.h\\"')]
-    )
+    config_path = "thirdparty/mbedtls/include/godot_module_mbedtls_config.h"
+    config_path = f"<{config_path}>" if env_mbed_tls["ninja"] and env_mbed_tls.msvc else f'\\"{config_path}\\"'
+    env_mbed_tls.Append(CPPDEFINES=[("MBEDTLS_CONFIG_FILE", config_path)])
 
     env_thirdparty = env_mbed_tls.Clone()
     env_thirdparty.disable_warnings()