diff --git a/Ghidra/Features/Python/src/main/java/ghidra/python/GhidraPythonInterpreter.java b/Ghidra/Features/Python/src/main/java/ghidra/python/GhidraPythonInterpreter.java
index 3d720cd85f..f6feac4f15 100644
--- a/Ghidra/Features/Python/src/main/java/ghidra/python/GhidraPythonInterpreter.java
+++ b/Ghidra/Features/Python/src/main/java/ghidra/python/GhidraPythonInterpreter.java
@@ -69,6 +69,11 @@ public class GhidraPythonInterpreter extends InteractiveInterpreter {
 				// Setup python cache directory
 				PythonUtils.setupPythonCacheDir(TaskMonitor.DUMMY);
 
+				// Enable protected java methods to be accessed from python sub-classes.
+				// This is necessary to be able to call protected GhidraScript/FlatProgram API
+				// methods from a python script.
+				System.setProperty("python.security.respectJavaAccessibility", "false");
+
 				// Indicate that we've initialized the python environment, which should
 				// only happen once.
 				pythonInitialized = true;
@@ -343,11 +348,12 @@ public class GhidraPythonInterpreter extends InteractiveInterpreter {
 				}
 			}
 
-			// Add public methods only once. Ignore inner classes.
+			// Add public and protected methods (only once). Ignore inner classes.
 			if (!scriptMethodsInjected) {
 				for (Method method : scriptClass.getDeclaredMethods()) {
 					if (!method.getName().contains("$") &&
-						Modifier.isPublic(method.getModifiers())) {
+						(Modifier.isPublic(method.getModifiers()) ||
+							Modifier.isProtected(method.getModifiers()))) {
 						method.setAccessible(true);
 						setMethod(script, method);
 					}